卢静
发布人:食品科学与工程学院  发布时间:2016-04-06   浏览次数:289


   

       卢静,吉林大学食品科学与工程学院食品质量与安全系教授,博士导师。主要从事食品安全与人体健康方面的研究工作。具体包括:天然植物提取物的活性和安全性、食品中的有害物质的安全性和营养干预、食品安全风险分析等研究工作,重点是对机体的脂质代谢及免疫功能的影响,相应成果发表在Food Chem ToxicolEnviron Toxicol Phar

MoleculesLat. Am. J.PharmImmunological InvestigationsImmunopharmacol Immunotoxicol,《食品科学》和《食品毒理学》等杂志。近几年来主持国家自然科学基金、吉林省科技厅、吉林省世行办等课题8项,发表文章30余篇,期中第一责任作者SCI 论文20篇。

学术任职:

       吉林省食品学会副理事

       中国毒理学会会员

学习工作经历:

       2015-现在 吉林大学食品科学与工程学院 教授

       2012-2013 美国康奈尔大学 食品科学系 访问学者

       2010-2014 吉林大学畜牧兽医学院兽医学博士后流动站 博士后

       2008-2014 吉林大学军需科技学院食品质量与安全系 副教授

       2006-2008 吉林大学军需科技学院食品质量与安全系 讲师

       2003-2006 吉林大学基础医学院生理学 博士

       2000-2003 长春中医学院内科学 硕士

       1995-2000 长春中医学院中医系 学士

在研项目:

[1]国家自然科学基金应急管理项目-长链非编码RNAs在二噁英(TCDD)诱导巨噬细胞向M2型分化型的作用(31540049

[2]十二五科技支撑项目-特种资源加工技术集成与产品(2013BAD16B09)(子课题)

[3] 吉林省科技厅重点课题-玉米汁中农药残留快速检测及控制技术的研究(3D512L776604)

[4]吉林省科技厅青年课题-Caco-2细胞单层模型和纳米金标记技术考察乳制品益生菌的安全性(20090146

[5]吉林省世行贷款农产品质量安全项目-吉林省养殖鱼类常见细菌性疾病联合用药研究(2011-YS9

[6]吉林大学科学前沿与交叉学科创新项目-长白山野菜短果茴芹降血脂活性及对AMPK信号转导通路的调控(450060445292

[7] 吉林大学种子基金-1,3-二氯丙醇(1,3-DCP)导致血脂紊乱的制研究(450060488105)

[8]国家自然科学基金重点项目-抗金葡菌a-溶血素活性化合物药效学研究(3A2110016603)(子课题)

发表论文:

[1]Lu, JingHuang, GuorenHu, SizhuoWang, ZhenningGuan, Shuang.3-Dichloro-2-propanol induced hyperlipidemia in C57BL/6J mice via AMPK signaling pathwayFood and Chemical Toxicology.64403-409,2014. (影响因子: 3.584).

[2]Jing LuGuoren Huang Shuang ZhangBocui SongZhenning WangLinli XuShuonan ZhangShuang Guan The inhibition of 2,3-dichloro-1-propanol on T cell in vitro and in vivo.International Immunopharmacology.172):321-328,2013. (影响因子: 2.551).

[3]Jing luRen MengrouFang BaochenHuang GuorenZhang ShuangWang YiDeng XumingGuan ShuangNonalcoholic fatty liver disease induced by 13-week oral administration of 1,3-dichloro-2-propanol in C57BL/6JmiceEnviron Toxicol Pharmacol.393):1115-1121,2015. (影响因子: 2.187).

[4]Jing luWang ZhenningRen MengrouFeng GuangxinYe BeiningWang

YiFang BaochenDeng XumingGuan Shuang A 4-week study of four

3-monochloropropane-1,2-diol diesters on lipid metabolism in C57BL/6J miceEnviron Toxicol Pharmacol.402):453-458, 2015. (影响因子: 2.187).

[5]Jing Lu Guoren HuangZhenning WangShuang ZhuangLinli XuBocui SongYing XiongShuang Guan Tyrosol exhibits negative regulatory effects on LPS response and endotoxemiaFood and Chemical Toxicology.62:172-1782013. (影响因子: 3.584).

[6]Guan S, Xiong Y, Song BC, Song Y, Wang DC, Chu X, Chen N, Huo MX, Deng XM, Lu J*. Protective effects of salidroside from Rhodiola rosea on LPS-induced acute lung injury in mice. Immunopharmacology and immunotoxicology. 34(4):667-672,2012. (影响因子: 1.829).

[7]J Lu, WH Qian, Ll Xu, GR Huang, W Cong, ZN Wang, XM Deng, DC Wang, S Guan. Phytochemical composition and toxicity of an antioxidant extract from Pimpinella brachycarpa(Kom.)Nakai. Environmental Toxicology and Pharmacology.34:409-415,2012. (影响因子: 1.593).

[8]J Lu, GR Huang, J Deng, WH Qian, LL Xu, C Wen, TT Li, ZN Wang, XM Deng, DC Wang, S Guan. Antioxidant and cytotoxic Activity of the Wild Edible Pimpinella brachycarpa ( Kom. ) Nakai. American Journal of Food Technolog. 7(8):494-500,2012.(EI)

[9]Soromou LW, Zhang ZC, Li RT, Chen N, Guo WX, Huo MX, Guan S, Lu J*, Deng XM. Regulation of Inflammatory Cytokines in Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage by 7-O-Methyl-naringenin. Molecules. 17 (3): 3574-3585,2012. (影响因子: 2.386)

[10]Jing Lu,Shuang Guan, Xue Shen, Wenhui Qian, Guoren Huang, Dacheng Wang, Xuming Deng, Guanghong Xie.Immunosuppressive activity of 8-gingerol on the immune responses in mice.Molecules. 22,16(3):2636-2645, 2011. (影响因子: 2.386).

[11]LuJing,GuanShuang,LiuJingbo, Guo Na, Shen Xue, Qian Wenhui, Deng Xuming. In vivo genotoxicity evaluation of crude extract from Ledum palustre and protective effects on cyclophosphamide-induced genotoxicity in mice.Lat. Am. J.Pharm.30 (1):112-118, 2011.(影响因子:0.309)

[12]Guan Shuang, Feng Haihua, Song Bocui, Guo Weixiao, Xiong Ying, Huang Guoren, Zhong Weiting,Huo Meixia,Chen Na,Lu, Jing*, Deng Xuming. Salidroside attenuates LPS-induced pro-inflammatory cytokine responses and improves survival in murine endotoxemia. International immunopharmacology. 11(12): 2194-2199, 2011. (影响因子:2.325).

[13]Shuang Guan, Yu Songa, Weixiao Guoa, Zhenguo Yang, Jing Lu*,XumingDeng. Immunosuppressive activity of Florfenicolon on the immune responses in mice.Immunological Investigations. 40(4):356-66,2011. (影响因子:1.466).

[14]Guan Shuang, Song Yu, Guo Weixiao, Chu Xiao, Zhang Xiaozhe, Wang Dacheng, Lu Jing*, Deng X.Immunosuppressiveactivity of tilmicosin on the immune responses in mice. Immunopharmacol Immunotoxicol. 33(2):323-328,2011. (影响因子:1.829).

[15]Shuang Guan, LuJing*, Weixiao Guo, Xuming Deng. Adjuvant effects of salidroside from Rhodiola rosea L.on the immune responses to ovalbumin in mice. Immunopharmacology And Immunotoxicology. 33(4): 738-743,2011 ( 影响因子:1.829).

[16]Shuang Guan, Jing Lu, Xue Shen, Wenhui Qian, Jingbo Liu, Xuming Deng. Florfenicol impairs the immune responses to vaccination against foot-and-mouth disease in mice.Immunopharmacology and immunotoxicology.33(4): 609-613,2011.(并列第一, 影响因子:1.829)

[17]Guan S, Wang W, Lu J, Qian W, Huang G, Deng X, Wang X.Salidroside attenuates hydrogen peroxide-induced cell damage through a cAMP-dependent pathway.Molecules. 19;16(4):3371-3379,2011.(并列第一, 影响因子: 2.386)

[18]Zhipeng YU,Wenzhu zhao,Jingbo Liu, Jing Lu, Feng Chen.QIGLF, a novel angiotensin -1 converting enzyme-inhibitory peptide from egg white protein.J Sci food Agric. 91(5):921-926, 2011 (影响因子:1.36)

[19]Liu Jing-bo, Yu Zhi-peng, Zhao Wen-zhu, Lu Jing, Chen Feng, Lin Song-yi. Liquid Chromatographic Assay of Peptides Activity with Inhibiting Angiotensin Converting Enzyme. Chem. Res. Chinese Universities. 26(5),712—716,2010.(影响因子:0.556)

[20]Qiu Jiazhang,Feng Haihua,Lu Jing,Xiang HuaWang Dacheng, Dong Jing, Wang Jianfeng,Wang XiaoliangLiu Juxiong, Deng Xuming.Eugenol Reduces the Expression of Virulence-related Exoproteins in Staphylococcus aureus. Applied and Environmental Microbiology. 76(17): 5846-5851,2010.(影响因子:3.686)

[21]Qiu Jiazhang, Feng Haihua, Xiang Hua, Wang Dacheng, Xia Lijie, Jiang Youshuai, Song Keji, Lu Jing, Yu Lu, Deng Xuming. Influence of subinhibitory concentrations of licochalcone A on the secretion of enterotoxins A and B by Staphylococcus aureus. FEMS Microbiol Lett.307(2):135-141,2010.(影响因子:2.199)

[22]Qiu Jiazhang, Wang Dacheng, Xiang Hua, Feng Haihua, Jiang Youshuai, Xia Lijie, Dong Jing, Lu Jing, Yu Lu, Deng Xuming. Subinhibitory Concentrations of ThymolReduce Enterotoxins A and B and alpha -Hemolysin Production in Staphylococcus aureus Isolates. PLoSONE. 5(3):e9736,2010.(影响因子:4.35)

编著情况:

[1]《食品毒理学》,副主编,东南大学出版社,20079.

[2]《食品质量与安全专业实验指导》,主编,吉林大学出版社,,20112.

联系方式:

联系电话:15948094141O

电子信箱:lu_jing@jlu.edu.cn,937434442@qq.com