关爽
发布人:食品科学与工程学院  发布时间:2016-06-21   浏览次数:99


    关爽,吉林大学军需科技学院食品质量与安全系讲师,主要从事食品免疫毒理学和安全评价的研究工作。几年来致力于天然植物提取物的免疫抗炎、抗氧化活性研究,相应成果发表在Arg.  and Food Toxi., Int Immunopharmacol, Molecules,Lat. Am. J.Pharm,Immunological  Investigations, Immunopharmacol  Immunotoxicol等SCI杂志。近几年来主持国家级课题一项(博士后科学基金面上一类资助801120106201);参与吉林省科技厅课题(用Caco-2细胞单层模型和纳米金标记技术考察乳制品益生菌的安全性20090146)、吉林省世行贷款农产品质量安全项目(吉林省养殖鱼类常见细菌性疾病联合用药研究2011-YS9)、吉林大学科学前沿与交叉学科创新项目(长白山野菜短果茴芹降血脂活性及对AMPK信号转导通路的调控450060445292)。近年来在国际杂志上发表多篇SCI  论文。

学术任职:

中国毒理学会会员

受教育经历(从大学本科开始,按时间倒排序)  


2009/09-2011/12 吉林大学  畜牧兽医学院基础兽医系 博士


2007/09-2009/06 吉林大学  军需科技学院食品科学系 硕士


1992/09-1996/06长春中医学院 中药系 学士  


研究工作经历(按时间倒排序)


2013/03-2013/11  美国康奈尔大学  农业与生命学院 食品系 访问学者


2012/05-现在    吉林大学  畜牧兽医学院(动物科学学院)生物化学与分子生物学 博士后


2012/02-现在     吉林大学军需科技学院食品质量与安全系 讲师


2000/02-2009/09 吉林亚泰药业 新药研发部  研究员


近几年发表论文

[1] Guan Shuang, Song Yu, Guo  Weixiao, Chu Xiao, Zhang Xiaozhe, Wang Dacheng, Lu Jing, Deng Xuming.  Immunosuppressive activity of tilmicosin on the immune responses in mice.  Immunopharmacol Immunotoxicol, 33(2), 323-8, 2011. (SCI收录)

[2] Shuang Guan, Yu Songa,  Weixiao Guoa, Zhenguo Yang, Jing Lu,Xuming Deng. Immunosuppressive activity of  Florfenicolon on the immune responses in mice. Immunological Investigations,  40(4), 356-66, 2011. (SCI收录)

[3] Guan Shuang, Feng Haihua,  Song Bocui, Guo Weixiao, Xiong Ying, Huang Guoren, Zhong Weiting, Huo Meixia,  Chen Na,Lu, Jing, Deng Xuming. Salidroside attenuates LPS-induced  pro-inflammatory cytokine responses and improves survival in murine endotoxemia.  International immunopharmacology,11(12), 2194-2199, 2011. (SCI收录)

[4] Shuang Guan, Lu Jing,  Weixiao Guo, Xuming Deng. Adjuvant effects of salidroside from Rhodiola rosea  L.on the immune responses to ovalbumin in mice. Immunopharmacology And  Immunotoxicology, 33 (4), 738-743, 2011. (SCI收录)

[5] Shuang Guan,Jing Lu, Xue  Shen, Wenhui Qian, Jingbo Liu, Xuming Deng. Florfenicol impairs the immune  responses to vaccination against foot-and-mouth disease in mice.  Immunopharmacology and immunotoxicology, 33 (4), 609-613, 2011. (SCI收录)  

[6] Guan S, Wang W, Lu J, Qian  W, Huang G, Deng X, Wang X. Salidroside attenuates hydrogen peroxide-induced  cell damage through a cAMP-dependent pathway. Molecules,16(4), 3371-9, 2011.  (SCI收录)

[7] Shuang Guan, Ying Xiong,  Bocui Song, Yu Song , Dacheng Wang, Xiao Chu, Na Chen, Meixia Huo, Xuming Deng ,  Jing Lu. Protective Effects of salidroside from Rhodiola rosea on LPS-Induced  Acute Lung Injury in Mice. Immunopharmacology and immunotoxicology, 34(4),  667-672, 2012. (SCI收录)

[8]Lanan Wassy Soromou, Rongtao  Li , Weixiao Guo , Weiting Zhong, Na Chen, Meixia Huo, Jing Lu, Shuang Guan*,  Xuming Deng, Regulation of inflammatory cytokines in  lipopolysaccharide-stimulated RAW 264.7 murine macrophage by  7-O-methylnaringenin. Molecules. 2011. (SCI收录)

[9] Jing Lu, Shuang Guan, Xue  Shen, Wenhui Qian, Guoren Huang, Dacheng Wang, Xuming Deng, Guanghong Xie.  Immunosuppressive activity of 8-gingerol on the immune responses in  mice.Molecules,16(3), 2636-45, 2011. (SCI收录,并列第一)

[10] Lu Jing , Guan Shuang, Liu  Jingbo, Guo Na, Shen Xue, Qian Wenhui, Deng Xuming. In vivo genotoxicity  evaluation of crude extract from Ledum palustre and protective effects on  cyclophosphamide-induced genotoxicity in mice. Lat. Am. J.Pharm, 30 (1),  112-118, 2010. (SCI收录,并列第一)

[11] Jing Lu, Wenhui Qian,  Linli Xua, Guoren Huang, Wen Cong, Zhenning Wang, Xuming Deng, Dacheng Wang,  Shuang Guan*. Phytochemical composition and toxicity of an antioxidant extract  from Pimpinella brachycarpa (Kom.) Nakai. Environmental toxicology  andpharmacology, 34, 409-415, 2012. (SCI收录)

[12]卢静,许琳莉,王振宁,丛雯,黄国任,卜秀娟,关爽*.1,3-DCP通过激活线粒体凋亡通路诱导HepG2细胞凋亡.  食品工业科技, 33(21), 81-84, 2012.

[13]卢静,沈雪,关爽,钱文辉,王璐,孙明辉,赵兴健.8-姜酚对小鼠脾淋巴细胞增殖和脾巨噬细胞吞噬作用的影响.毒理学杂志,  24(5), 398-400, 2010.


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