主讲《食品免疫学》、《食品毒理学》等课程。
邮箱:liren77@jlu.edu.cn
办公室:吉林大学和平校区食品学院(管理楼)207室
教育经历
2013.11–2016.04 俄亥俄州立大学Wexner医学中心, 内科医学部,免疫学专业,联合培养博士
2011.09–2016.06 吉林大学生命科学学院,分子酶学工程教育部重点实验室,细胞生物学专业,博士
2007.09–2010.06 吉林农业大学生命科学学院,生物技术专业,硕士
2003.09–2007.06 吉林农业大学生命科学学院,生物技术专业,理学学士
工作经历
2020.09–至今 吉林大学,食品科学与工程学院,副教授/硕士生导师
2019.09–2020.09 吉林大学食品科学与工程学院,讲师
2016.09–2019.09 吉林大学无机合成与制备化学国家重点实验室,师资博士后
主持或参加科研项目(课题)情况
1. 吉林省教育厅“十三五”科学技术项目,增强白血病药物疗效的肠道微生物的鉴定及免疫调控机制研究,2019-2020,已结题,主持。
2. 中国博士后科学基金面上项目,二氧化硅纳米载药体系的构建及抗白血病耐药机制研究,2018-2019,已结题,主持。
3. 国家自然科学基金面上项目,膜型基质金属蛋白酶靶向多肽探针在肿瘤影像中的研究,2014-2017,已结题,第一参加人。
4. 企业技术开发委托,横向,开发改善慢性腹泻的新型益生菌饮品(3R119H124071),在研,主持。
近三年代表作(限10篇)
1. Jie Zhang, Petr Pavek, Rajamanikkam Kamaraj, Li Ren*, Tiehua Zhang*. Dietary phytochemicals as modulators of human pregnane X receptor. Critical Reviews in Food Science and Nutrition, 2023, 63(19): 3279-3301. (1区IF=10.2)
https://doi.org/10.1080/10408398.2021.1995322
2. Yuan Liang, Qiuyan Jiang, Haoyang Zou, Jingqi Zhao, Jie Zhang*, Li Ren*. Withaferin A: a potential selective glucocorticoid receptor modulator with anti-inflammatory effect. Food and Chemical Toxicology, 2023, 179: 113949. (1区IF=4.3)
https://doi.org/10.1016/j.fct.2023.113949
3. Haoyang Zou, Yiyao Gong, Haiqing Ye, Cuiping Yuan, Tiezhu Li, Jie Zhang*, Li Ren*. Dietary regulation of peroxisome proliferator-activated receptors in metabolic syndrome. Phytomedicine, 2023, 116: 154904. (1区IF=7.9)
https://doi.org/10.1016/j.phymed.2023.154904
4. Li Ren#, Haoge Luo#, Jingqi Zhao, Shuqing Huang, Jie Zhang*, Chen Shao*. An integrated in vitro/in silico approach to assess the anti-androgenic potency of isobavachin. Food and Chemical Toxicology, 2023, 176: 113764. (1区IF=4.3)
https://doi.org/10.1016/j.fct.2023.113764
5. Jingqi Zhao, Yantong Sun, Cuiping Yuan, Tiezhu Li, Yuan Liang, Haoyang Zou, Jie Zhang*, Li Ren*. Quercetin ameliorates hepatic fat accumulation in high-fat diet-induced obese mice via PPARs. Food & Function, 2023, 14(3): 1674-1684. (1区IF=6.1)
https://doi.org/10.1039/D2FO03013F
6. Haoyang Zou, Haiqing Ye, Jie Zhang*, Li Ren*. Recent advances in nuclear receptors-mediated health benefits of blueberry. Phytomedicine, 2022, 100: 154063. (1区IF=7.9)
https://doi.org/10.1016/j.phymed.2022.154063
7. Li Ren, Jie Zhang*, Tiehua Zhang*. Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells. Food Chemistry, 2021, 340: 127933. (1区IF=8.8) 高被引论文
https://doi.org/10.1016/j.foodchem.2020.127933
8. Yuan Liang, Tiehua Zhang, Jingqi Zhao, Chenfei Li, Haoyang Zou, Fangyu Li, Jie Zhang*, Li Ren*. Glucocorticoid receptor-mediated alleviation of inflammation by berberine: in vitro, in silico and in vivo investigations. Food & Function, 2021, 12(23): 11974-11986. (1区IF=6.1)
https://doi.org/10.1039/D1FO01612A
9. Tianzhu Guan#, Guangjie Zhang#, Yantong Sun, Jie Zhang*, Li Ren*. Preparation, characterization, and evaluation of HP-β-CD inclusion complex with alcohol extractives from star anise. Food & Function, 2021, 12(20): 10008-10022. (1区IF=6.1)
https://doi.org/10.1039/D1FO02097H
10. Jie Zhang, Jiarui Zhao, Yantong Sun, Yuan Liang, Jingqi Zhao, Haoyang Zou, Tiehua Zhang, Li Ren*. GR-mediated anti-inflammation of α-boswellic acid: Insights from in vitro and in silico studies. Food and Chemical Toxicology, 2021, 155: 112379. (1区IF=4.3)
https://doi.org/10.1016/j.fct.2021.112379