房天琪,出生年月:1987.06.14,女,职称:副教授,学位:工学博士,近年来主要围绕“天然化合物是如何发挥抗细菌感染作用”这一科学问题开展了系列研究,发现多种天然化合物以细菌溶血素、分选酶和凝固酶等重要毒力因子和NDM、MCR等重要耐药酶为靶标,抑制细菌致病性和耐药性,为天然化合物抗细菌感染的食品防腐剂研发提供了良好的基础。先后承担国家自然科学基金青年基金项目、企业合作横向课题等项目,以第一或通讯作者(含并列)在领域内知名期刊British Journal of Pharmacology和Journal of dairy science等发表学术论文10余篇,国家授权发明专利2项。电子邮箱:fangtianqi0527@126.com 办公室电话:18686633437
1.教育经历:(时间由近及远)
2013/09---2019/12 吉林大学 食品科学专业(博士)
2009/09---2012/06 长春工业大学 食品科学专业(硕士研究生)
2005/09---2009/06 长春工业大学 食品科学与工程专业(本科)
2.工作经历:(时间由近及远)
2020/08---2021/12 吉林大学动物医学学院 博士后
2021/12---至今 吉林大学食品科学与工程学院 讲师
3.代表性学术成果:(项目限制10项,论文限制10篇)
(1) Fang TQ, Shen X, Guo MR.*, Physiochemical, texture properties and microstructure of yogurt using polymerized whey protein directly prepared from cheese whey as thickening agent. Journal of Dairy Science, 2019, 102,7884-7894. (1区TOP期刊,IF=4.034)
(2) Fang TQ, Shen X, Hou JC, Guo MR.*, Effects of polymerized whey protein prepared directly from cheese whey as fat replacer on physiochemical, texture, microstructure and sensory properties of low-fat set yogurt. LWT-Food Science and Technology, 2019,115, 108268. (1区TOP期刊,IF=4.952)
(3) Wang GZ, Gao YW, Wu XH, Gao X, Zhang M, Liu HM* and Fang TQ*. Inhibitory effect of piceatannol on Streptococcus suis infection both in vitro and in vivo. Frontiers in microbiology. 2020, 593588. (2区TOP期刊,IF =5.640)
(4) Lv HF#, Fang TQ#, Kong FR, Wang JF, Deng XM, et al. Dryocrassin ABBA ameliorates Streptococcus pneumoniae-induced infection in vitro through inhibiting Streptococcus pneumoniae growth and neutralizing pneumolysin activity. MICROBIAL PATHGENESIS 2020. 104683.. (3区,IF =3.738)
(5) Shen X#, Fang TQ#, Zheng J, Guo MR.*, Physicochemical properties and cellular uptake of astaxanthin-loaded emulsions, Molecules. 2019,24,727 (3区,IF =4.411)
(6) Shen X, Fang TQ, Gao F, Guo MR.*, Effects of ultrasound treatment on physicochemical and emulsifying properties of whey proteins pre- and post-thermal aggregation. Food Hydrocolloids. 2017, 63, 668-676. (1区,IF =5.0889)
(7) Wang TT#, Fang TQ#,Wang XY, Zhang C, Shen X, Deng XM*, Wang JF*, Amentoflavone attenuated Listeria monocytogenes pathogenlcity through an LLO-dependent mechanism, British journal of pharmacology, ID: 2021-BJP-0960-RP. (1区TOP,IF=8.739).
(8) Xie SN#, Li L#, Baihe Zhan, Xue Shen, Xuming Deng, Wenxi Tan*, Fang TQ*, Pogostone enhances the antibacterial activity of colistin against MCR-1-positive bacteria by inhibiting the biological function of MCR-1. Frontiers in microbiology, 2021 (2区TOP期刊,IF =5.640)
(9) Can Zhang#, Xinyu Wang#, Linlin Shi, Baihe Zhan, NaNa Hou, Suohong Liu, Manjie Bao, Gefu Chi1, Tianqi Fang*,Alnustone inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortaseA. MICROBIAL PATHOGENESIS (3区,IF =3.738)
(10) Linlin Shi#, Fang TQ#, Can Zhang, Xuming Deng, Yonglin Zhou*, Jianfeng Wang*, High-protein compound yogurt with quinoa ameliorated Nonalcoholic Fatty Liver Disease in mice through the modulation of intestinal microecology, Journal of Dairy Science. 2023,8(106),5309-5327. (1区TOP期刊,IF=4.034)
4. 授权专利(限制10项)
(1)乳清蛋白聚合反应器,授权号ZL 201521097379.9